Those taking omeprazole have been warned they could be undermining the medication's effectiveness through other substances entering their system. The proton pump inhibitor (PPI) is widely prescribed across the UK for ailments including heartburn, stomach ulcers, and gastro-oesophageal reflux disease (GERD).

The drug functions by decreasing stomach acid levels and comes in multiple forms, such as capsules, tablets, or liquid. Health guidance typically advises against taking omeprazole beyond a fortnight when bought over the counter, owing to possible adverse effects.

Nevertheless, based on how severe your condition is, a GP might suggest continuing the treatment for an extended duration via prescription. NHS guidance emphasises that if you are on multiple different medications, certain ones might interfere with omeprazole.

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The NHS UK site states: "There are some medicines, remedies and supplements that may not mix well with omeprazole."

Interactions with different drugs could affect the effectiveness of omeprazole. Moreover, omeprazole may also cause certain medications to lose their efficacy or function differently than initially designed.

The NHS warns that amongst the drugs you might need to steer clear of whilst on omeprazole are:

• Lansoprazole


• Famotidine


• Diazepam


• Warfarin


• Clopidogrel


• Digoxin


• Phenytoin


• St John's Wort


• Atazanavir


• Nelfinavir

It is crucial to remember that it is generally advised to steer clear of alcohol whilst on omeprazole. This is due to the fact that alcohol can amplify the amount of acid in your stomach, potentially exacerbating the symptoms you are using omeprazole to alleviate.

Bear in mind that this is not an exhaustive list of medications that may interact with omeprazole. If you have been prescribed omeprazole, the NHS recommends consulting a doctor or pharmacist if you're also taking any other medicines, vitamins, supplements, or herbal remedies.

The packet or leaflet accompanying your omeprazole should provide additional information on potential interactions. If you're uncertain about the safety of taking omeprazole, it's best to consult a pharmacist or doctor.

Further details on the NHS website can be found here.