Omeprazoleis prescribed to treat common conditions such as heartburn, indigestion andacid reflux,but prolonged or frequent use of the medication can trigger a variety of problems. According to one gut health specialist, some of these issues can manifest on your skin.


Dr Sari Arponen, an expert in gut microbiota, cautioned that omeprazole and other widely-used medications could be responsible for certain skin complaints. Speaking on COPE Cool, the specialist outlined how our gut health can influence the condition of our skin and provide clues about what's occurring inside our bodies.


She even proposed: "Skin treatment could involve personalised analyses of the microbiota."



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Gut health depends on a carefully balanced population of various bacteria types, which is essential for our digestion, immune system and metabolism. When the bacteria is properly balanced, the skin remains more hydrated and regenerates effectively because the gut transmits "calming, anti-inflammatory signals".



When these bacteria become imbalanced, it can result in inflammation and associated skin problems. The doctor noted that rosacea, which causes facial redness and bumps, is typically associated with an excessive amount of a particular bacteria in the small intestine.


The chronic condition isn't contagious and is generally triggered by factors such as sunlight, stress, alcohol, hot weather or drinks. Atopic dermatitis, the most prevalent type of eczema, is associated with a diminished diversity of gut bacteria, according to the doctor.


Acne is also connected to low-grade inflammation related to intestinal health. This delicate link between gut bacteria and skin conditions means that medications like omeprazole, which can alter the population of gut bacteria, may result in skin problems. She said: "Omeprazole and related medications, can cause many problems by significantly altering the stomach's pH."


Dr Arponen cautioned that omeprazole and other proton pump inhibitors often alter the pH levels in your digestive system, which can affect the balance or biodiversity of your gut bacteria.


She advised people to take the medication under medical supervision and suggested the possible use of probiotics to mitigate the adverse effects of these drugs.


The gut-skin connection can also be influenced by our diet. Substances such as sugar, additives and ultra-processed foods are known as pro-inflammatory ingredients, triggering a chain reaction in the gut and skin.


Conversely, foods rich in polyphenols, fibre and quality fats create a protective environment for both systems. This includes most foods found in the Mediterranean diet.


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