Researchers at the University of Chicago have found that zeaxanthin, a plant-based carotenoid used for eye health, may also strengthen cancer-fighting CD8+ T cells and improve immunotherapy outcomes, according to a study reported by ANI from Cell Reports Medicine. In mouse and lab studies, it enhanced tumour-killing activity and boosted immune signalling, especially with checkpoint inhibitors.

Washington: The researchers at the University of Chicago have uncovered a surprising new role for zeaxanthin, a plant-based compound best known for supporting eye health.

According to findings published in Cell Reports Medicine, this common carotenoid may also help the immune system fight cancer by enhancing the activity of key immune cells.

The discovery points to zeaxanthin as a simple, widely available supplement that could improve how well cancer immunotherapies work.

"We were surprised to find that zeaxanthin, already known for its role in eye health, has a completely new function in boosting anti-tumor immunity," said Jing Chen, PhD, Janet Davison Rowley Distinguished Service Professor of Medicine and senior author of the study.